Acrylic acids and derivatives
Apexbio Technology LLC KW-2478 819812-04-9 100mg
KW-2478 (CAS 819812-04-9) is a potent non-ansamycin inhibitor of heat shock protein 90 (Hsp90) Unlike traditional Hsp90 inhibitors such as 17-AAG KW-2478 exhibits improved aqueous solubility and reduced hepatotoxicity In multiple myeloma cell models KW-2478 induces degradation of Hsp90 client proteins and leads to downregulation of IgH translocation products including FGFR3 c-Maf and cyclin D1 thereby inhibiting cell proliferation and promoting apoptosis Additionally KW-2478 reduces levels of Cdk9 and phosphorylated 4E-BP1 further suppressing oncogenic transcriptional regulators This compound is a valuable tool for studying Hsp90-mediated pathways and evaluating therapeutic strategies in hematological malignancies
Enzo Life Sciences Isradipine (10mg). CAS: 75695-93-1
Potent and selective L-type calcium channel blocker. A clinically useful antihypertensive agent which has anti-atherosclerotic effects and improves endothelium-mediated NO-dependent vasodilation. Displays neuroprotective activity in a rat model of focal ischemia. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25 mg/ml) or 100% ethanol (15 mg/ml). Long Term Storage: +4°C.
eMolecules 189954-96-9 | Medchem Express | Firocoxib | 5mg | 446264443 | HY-14670 | MFCD09837800 | 336.4 | C17H20O5S
Medchem Express | HUP30 | 5mg | 785215260 | HY-129088 | 312747-21-0 | MFCD00412124 | 305.350 | C14H15N3O3S
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Medchemexpress LLC Elaiophylin | 37318-06-2 | C54H88O18 | 5 MG
Elaiophylin is an autophagy inhibitor that exhibits antitumor activity in ovarian cancer cells. With a molecular weight of 1025.27, it appears as a white to off-white solid and is intended for research use only.
- Autophagy inhibitor
- Exhibits antitumor activity in ovarian cancer cells
- Molecular weight of 1025.27
- White to off-white solid appearance
- Soluble in DMSO for in vitro experiments
- Affects ovarian cancer cell survival during hypoxia
- Leads to activation of cleaved CASP9/caspase-9 and PARP1
- Downregulates BIRC5/survivin
- Suppresses ovarian cancer SKOV3 cell growth in athymic mice
- Achieves significant antitumor effects without toxicity at lower doses
Matrix Scientific 1,1,1,3,3,3-HEXAFLUOROISOP-25G
1, 1,1,3,3,3-Hexafluoroisopropyl acrylate, 99%; 25g,C6H4F6O2, MFCD00040104, mw 222.09, [2160-89-6]
eMolecules 630-94-4 | Medchem Express | Corynoxeine | 5mg | 446275186 | HY-N0590 | MFCD20527288 | 382.46 | C22H26N2O4
Medchem Express | Corynoxeine | 5mg | 446275186 | HY-N0590 | 630-94-4 | MFCD20527288 | 382.460 | C22H26N2O4
eMolecules 63644-62-2 | Medchem Express | Coniferyl ferulate | 1mg | 582658851 | HY-N1916 | MFCD13195559 | 356.374 | C20H20O6
Medchem Express | Coniferyl ferulate | 1mg | 582658851 | HY-N1916 | 63644-62-2 | MFCD13195559 | 356.374 | C20H20O6
eMolecules 54350-48-0 | Medchem Express | Etretinate | 10mg | 446273333 | HY-B0797 | MFCD00866624 | 354.49 | C23H30O3
Medchem Express | Etretinate | 10mg | 446273333 | HY-B0797 | 54350-48-0 | MFCD00866624 | 354.490 | C23H30O3
Medchemexpress LLC (2-Hydroxypropyl)-α-cyclodextrin (MW 1180) | 128446-33-3 | 1180 (Average) | 500 MG
(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) is a cyclic oligosaccharide derivative that acts as a solubilizer in various experiments. For research use only.
- Appearance: Solid
- Color: White to off-white
- Solubility (In vitro): H2O : 100 mg/mL (Need ultrasonic)
Medchemexpress LLC Salvianolic acid Y | 1638738-76-7 | 5 MG
Salvianolic acid Y is a phenolic acid sharing the same planar structure as Salvianolic acid B. It is known for its ability to rescue cell injury caused by H2O2. In vitro studies demonstrate that Salvianolic acid Y provides protection against hydrogen peroxide (H2O2)-induced cell lesions.
- Shares planar structure with Salvianolic acid B
- Rescues cell injury induced by H2O2
- Offers 54.2% protection rate in rat PC12 cells against H2O2-induced lesions
- Intended for research use only
Matrix Scientific 1H,1H,7H-DODECAFLUOROHEPTYL ACRYLATE MF C10H6F12O2 MW 386.14 CAS 2993-85-3 MDL MFCD00080746 QTY 5 UOM G
1H,1H,7H-DODECAFLUOROHEPTYL ACRYLATE MF C10H6F12O2 MW 386.14 CAS 2993-85-3 MDL MFCD00080746 QTY 5 UOM G
Sigma Aldrich Fine Chemicals Biosciences Isradipine >=98% (HPLC), solid | 75695-93-1 | MFCD00153820 | 5MG
Isradipine >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 371.39 | 75695-93-1 | MFCD00153820 | 5MG
Pfaltz & Bauer 2-Hydroxyethyl acrylate 97% 250G | 818-61-1
2-Hydroxyethyl acrylate 97% 250G | 818-61-1
Enzo Life Sciences Parthenolide (250 mg). CAS: 20554-84-1
Sesquiterpene lactone. Widely used as an herbal remedy for arthritis and migraine. Has anti-inflammatory, antisecretory and spasmolytic activity. Specifically inhibits activation of NF-κB by preventing the degradation of IκBα and IκBβ. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Inhibits tubulin carboxypeptidase (TCP) activity. Alternative name: (1aR-[1aR*,4E,7aS*,-10aS*,-10bR*])-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclo deca[1,2-b]furan-9(1aH)-one. Purity: ≥97% (HPLC, TLC). Solubility: Soluble in DMSO (100mg/ml), dichloromethane (50mg/ml) or 100% ethanol (20mg/ml). Long Term Storage: -20°C.
eMolecules L-Ascorbyl 6-stearate | 10605-09-1 | MFCD00059739 | 1g
Combi-Blocks | L-Ascorbyl 6-stearate | 1g | 205391317 | OR-5973 | 95.000 | 10605-09-1 | MFCD00059739 | 442.593 | C24H42O7
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